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20 Common Causes of Edema: Understanding the Factors Behind Swelling

September 5, 2025 by Zara Jamshed

Edema, a condition characterized by swelling caused by fluid retention in body tissues, can occur for various reasons.

When excess fluid accumulates, it can lead to discomfort, restricted mobility, and potentially serious complications if left untreated. Treating edema is important to alleviate symptoms and prevent further health issues.

In this article, we explore 20 common causes of edema, ranging from medical conditions like heart failure and kidney disease to lifestyle factors such as prolonged immobility and malnutrition.

Understanding these causes can help individuals recognize and address underlying issues contributing to their edema, facilitating proper treatment and management.

By addressing the root causes of edema, individuals can improve their quality of life and reduce the risk of complications associated with this condition.

Here are the 5 common causes of edema:

  • Heart failure
  • Kidney disease
  • Liver disease
  • Chronic venous insufficiency
  • Diabetes

Causes of Edema infographic

1. Heart Failure

Heart failure happens when the heart isn’t able to pump blood as well as it should. This can be due to damage from heart attacks, high blood pressure, or other conditions.

When the heart doesn’t pump blood effectively, fluid can build up in the body, leading to symptoms like swelling in the legs, ankles, or abdomen. This swelling is called edema.

For example, someone with heart failure might notice that their shoes feel tight or that they have to loosen their belt. To treat heart failure and reduce edema, doctors often recommend medications like diuretics to help the body get rid of excess fluid.

They may also suggest lifestyle changes like reducing salt intake and exercising regularly to improve heart function.

In severe cases, other treatments like surgery or implantable devices may be needed to manage heart failure and its symptoms.

2. Kidney Disease

When the kidneys are damaged and can’t filter blood properly, it leads to kidney disease. This can happen due to conditions like diabetes or high blood pressure. Symptoms may include

  • Swelling in legs, hands, or face: Indicates fluid retention in tissues.
  • Fatigue: Feeling excessively tired, often due to underlying health issues.
  • Changes in urination: Altered frequency or appearance of urine, signaling potential kidney problems.

The kidneys play an important role in regulating fluid balance in the body. When they’re not functioning properly, fluid can accumulate, leading to edema.

For example, someone with kidney disease might notice puffiness around their eyes or swelling in their ankles.

Treatment often involves medications to manage blood pressure and control fluid levels, along with dietary changes to reduce stress on the kidneys.

3. Liver Disease

Liver disease can be caused by various factors such as excessive alcohol consumption or viral infections. Symptoms may include abdominal swelling, jaundice, and fatigue.

When the liver is damaged, it can’t produce enough protein to keep fluid in the blood vessels, leading to fluid leakage into the surrounding tissues and causing edema.

For example, someone with liver disease might develop swelling in their abdomen, known as ascites.

Treatment involves addressing the underlying cause of liver damage, such as abstaining from alcohol or taking antiviral medications, along with medications to manage fluid buildup.

4. Chronic Venous Insufficiency

Chronic venous insufficiency occurs when the veins in the legs don’t work properly, leading to blood pooling in the lower extremities.

Symptoms may include swollen ankles, leg cramps, and skin changes. When blood doesn’t flow well back to the heart, pressure builds up in the veins, causing fluid to leak out into the surrounding tissues and resulting in edema.

For instance, someone with chronic venous insufficiency might experience swelling in their legs after standing for long periods.

Treatment often involves wearing compression stockings, elevating the legs, and sometimes surgery to improve vein function.

Woman Having Pain In Her Ankle

5. Pregnancy

During pregnancy, hormonal changes and the growing uterus can put pressure on blood vessels, leading to fluid retention. Symptoms may include

  • Swollen Feet
  • Swollen hands
  • Swollen face
  • Weight gain

As the body retains more fluid during pregnancy, it can cause edema in various parts of the body. For example, pregnant women may notice swelling in their ankles and fingers.

Treatment usually involves lifestyle modifications like resting with feet elevated, avoiding standing for long periods and wearing support stockings.

In severe cases, doctors may prescribe diuretics to reduce fluid retention, but this is typically avoided unless necessary due to potential risks to the baby.

Regular prenatal check-ups are important for monitoring edema and ensuring both the mother and baby are healthy.

6. Medications (such as calcium channel blockers or NSAIDs)

Some medications, like calcium channel blockers used to manage high blood pressure or NSAIDs (nonsteroidal anti-inflammatory drugs) for pain relief, can trigger edema as a side effect.

These drugs disrupt the body’s usual fluid balance, leading to fluid retention in tissues. For example, calcium channel blockers relax the muscles in blood vessel walls, causing fluid to leak into surrounding tissues and result in swelling.

Similarly, NSAIDs may interfere with kidney function, leading to fluid buildup. Treatment involves consulting a doctor to adjust medication dosage or switch to alternative drugs that don’t cause edema.

It’s important to monitor for symptoms such as swelling in the ankles or hands and report them promptly to healthcare providers.

7. Lymphedema

Lymphedema arises when there’s a blockage in the lymphatic system, hindering the proper drainage of lymph fluid. This blockage may occur due to surgical procedures, trauma, infection, or congenital conditions.

Symptoms typically include swelling in one arm or leg, accompanied by feelings of heaviness or tightness.

For instance, after cancer treatment involving the removal of lymph nodes, lymphedema may develop as a long-term consequence.

Treatment involves wearing compression garments, undergoing manual lymphatic drainage therapy, and performing exercises to encourage fluid movement and reduce swelling.

8. Infections (such as cellulitis)

Infections like cellulitis can induce edema by provoking inflammation and fluid accumulation in affected areas.

For example, a bacterial skin infection like cellulitis can trigger an immune response, causing blood vessels to dilate and become leaky. This allows fluid and white blood cells to accumulate in tissues, resulting in swelling.

Prompt treatment with antibiotics is important to control the infection and reduce swelling. Additionally, elevating the affected area and applying warm compresses may help alleviate symptoms.

It’s important to seek medical attention if symptoms worsen or if fever develops, as untreated infections can lead to severe complications.

9. Deep Vein Thrombosis (DVT)

Deep vein thrombosis occurs when a blood clot forms in one of the deep veins, usually in the legs.

This clot can partially or completely block blood flow, leading to swelling, pain, and sometimes even a life-threatening condition called pulmonary embolism if the clot breaks loose and travels to the lungs. Risk factors for DVT include:

  • Prolonged immobility: Long periods of sitting or lying down without movement.
  • Surgery: Procedures that disrupt normal blood flow.
  • Injury: Trauma to the veins, causing damage.
  • Pregnancy: Increased pressure on pelvic and leg veins.
  • Hormonal birth control: Altered clotting mechanisms.
  • Certain medical conditions: Disorders affecting blood clotting or vessel inflammation.

Symptoms of DVT include swelling, pain, tenderness, and warmth in the affected leg. Prompt diagnosis and treatment are essential to prevent complications.

Treatment typically involves blood-thinning medications to dissolve the clot and prevent new clots from forming, along with measures to reduce swelling and prevent further complications.

10. Hypothyroidism

Hypothyroidism is a condition in which the thyroid gland doesn’t produce enough thyroid hormone. Thyroid hormone plays an important role in regulating metabolism, energy levels, and various bodily functions.

When levels of thyroid hormone are low, it can slow down metabolism and lead to a range of symptoms, including fatigue, weight gain, cold intolerance, dry skin, hair loss, and muscle weakness.

In some cases, hypothyroidism can also cause fluid retention and edema, particularly in the face, hands, and feet.

This occurs because reduced thyroid hormone levels can disrupt the balance of salt and water in the body, leading to fluid accumulation in tissues.

Treatment typically involves taking synthetic thyroid hormone medication to restore hormone levels to normal.

11. Malnutrition

Malnutrition can lead to edema due to a lack of essential nutrients needed for maintaining proper fluid balance in the body.

For instance, a deficiency in protein or micronutrients can weaken blood vessel walls and impair the body’s ability to regulate fluid levels, resulting in swelling, especially in the legs and abdomen.

Symptoms of edema due to malnutrition may include swollen limbs, fatigue, and weight loss.

Treatment involves addressing the underlying cause of malnutrition through dietary changes, nutritional supplements, and medical intervention if necessary.

12. Preeclampsia

Preeclampsia, a serious pregnancy complication, can cause edema due to increased blood pressure and damage to blood vessels and organs.

For example, elevated blood pressure can impair kidney function, leading to fluid retention and swelling, particularly in the hands and face.

Symptoms of preeclampsia-related edema may include rapid weight gain, swelling in the hands and face, headaches, and visual disturbances.

Treatment involves close monitoring by healthcare providers, blood pressure management, and sometimes early delivery of the baby to prevent complications for both mother and child.

13. Protein Deficiency (Hypoalbuminemia)

Protein deficiency, specifically hypoalbuminemia, can lead to edema as albumin, a protein in the blood, helps maintain fluid balance.

For instance, low levels of albumin can result in fluid leaking from blood vessels into surrounding tissues, causing swelling, especially in the legs and abdomen.

Symptoms of edema due to protein deficiency may include swollen limbs, fatigue, and changes in urine output.

Treatment involves addressing the underlying cause of protein deficiency, such as malnutrition or liver disease, through dietary changes, nutritional supplements, and medical interventions like albumin infusions in severe cases.

14. Diabetes

Diabetes can cause edema through various mechanisms, including damage to blood vessels and impaired kidney function.

For example, diabetes-related kidney disease can lead to protein leakage into the urine and fluid retention, resulting in swelling, particularly in the legs and ankles.

Symptoms of diabetes-related edema may include swollen extremities, changes in urine output, fatigue, and unexplained weight gain.

Treatment involves managing blood sugar levels through medication, diet, and lifestyle changes, along with addressing complications like kidney disease through medication and close monitoring by healthcare providers.

15. Allergic Reactions

Allergic reactions can trigger edema due to the release of histamine and other inflammatory substances in response to allergens.

For example, in cases of allergic rhinitis, swelling in the nasal passages can occur, leading to congestion and difficulty breathing.

Symptoms of edema from allergic reactions may include swelling, itching, redness, and difficulty breathing.

Treatment involves identifying and avoiding allergens when possible, along with using antihistamines or other medications to reduce inflammation and swelling.

Women Swollen Nasal Due To Allergy

16. Trauma or Injury

Trauma or injury to the body can lead to edema as a part of the healing process. For instance, swelling often occurs around a sprained ankle or after surgery due to increased blood flow and leakage of fluid from damaged blood vessels.

Symptoms of edema from trauma or injury may include localized swelling, pain, tenderness, and restricted movement.

Treatment involves rest, elevation, ice, compression, and sometimes anti-inflammatory medications to reduce swelling and promote healing.

17. Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) can cause edema due to fluctuations in blood oxygen levels during episodes of interrupted breathing during sleep.

For example, fluid retention in the legs may occur as a result of changes in circulation and increased pressure on blood vessels.

Symptoms of edema from obstructive sleep apnea may include swelling in the legs, especially upon waking, along with daytime fatigue, snoring, and pauses in breathing during sleep.

Treatment involves using continuous positive airway pressure (CPAP) therapy to keep the airway open during sleep, along with lifestyle changes such as weight loss and avoiding alcohol and sedatives before bedtime.

18. Cirrhosis

Cirrhosis, a late stage of liver disease, can lead to edema due to impaired liver function and changes in blood flow through the liver.

For example, fluid can accumulate in the abdomen (ascites) or legs (peripheral edema) due to increased pressure in the blood vessels.

Symptoms of edema from cirrhosis may include abdominal swelling, leg swelling, fatigue, and loss of appetite.

Treatment involves managing the underlying liver disease through medications, lifestyle changes, and sometimes procedures such as paracentesis to remove excess fluid from the abdomen.

Additionally, dietary restrictions and avoiding alcohol are important aspects of managing cirrhosis-related edema.

19. Certain Cancers (such as Lymphoma)

Certain cancers, including lymphoma, can lead to edema due to various factors such as tumor growth, inflammation, and disruption of lymphatic drainage.

For example, lymphoma tumors can obstruct lymphatic vessels, causing fluid buildup and swelling in nearby tissues.

Symptoms of edema from cancer may vary depending on the location and stage of the disease but can include swelling, pain, and discomfort.

Treatment involves addressing the underlying cancer through chemotherapy, radiation therapy, surgery, or other targeted therapies.

Additionally, managing symptoms such as edema may involve medications to reduce inflammation and swelling, as well as supportive care measures.

20. Inflammatory Conditions (such as Rheumatoid Arthritis)

Inflammatory conditions like rheumatoid arthritis (RA) can lead to edema due to chronic inflammation and immune system dysfunction.

For example, in RA, inflammation in the joints can lead to synovial fluid accumulation, causing joint swelling and stiffness.

Symptoms of edema from inflammatory conditions may include swollen and tender joints, stiffness, and reduced range of motion.

Treatment involves managing inflammation through medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biological therapies.

Physical therapy and lifestyle modifications may also help reduce swelling and improve joint function.

Conclusion 

In conclusion, edema can arise from various factors, including medical conditions, lifestyle choices, and environmental factors. Identifying the underlying cause of edema is essential for effective treatment and management.

Whether it’s addressing heart failure, kidney disease, or simply making lifestyle changes like avoiding prolonged sitting or improving nutrition, understanding the root causes allows individuals to take proactive steps toward alleviating swelling and improving overall health.

By addressing these causes, individuals can work towards reducing edema, enhancing mobility, and maintaining a better quality of life.

Causes of Edema FAQs 

1. What is edema?

Edema is a condition where excess fluid accumulates in body tissues, causing swelling and puffiness.

2. What are the common causes of edema?

Common causes include heart failure, kidney disease, pregnancy, and certain medications that affect fluid balance.

3. How does edema affect the body?

Edema can lead to discomfort, restricted movement, and complications like skin ulcers or difficulty breathing if left untreated.

4. Can edema be a sign of a serious medical condition?

Yes, edema can indicate underlying health issues like heart or kidney problems, which require medical attention.

5. Are there lifestyle factors that contribute to edema?

Yes, factors such as prolonged sitting, standing, or a high-salt diet can contribute to fluid retention and edema formation.

6. How is edema diagnosed?

Diagnosis often involves a physical examination, medical history review, and sometimes imaging tests like ultrasound or MRI scans.

7. What are the treatment options for edema?

Treatment may include medications to reduce fluid retention, lifestyle changes such as dietary modifications, compression therapy, or addressing underlying health conditions.

8. Is edema preventable?

While some causes of edema may not be preventable, maintaining a healthy lifestyle, including regular exercise and a balanced diet, can help reduce the risk.

Resources Used For The Research:

  • WebMD
  • Cleveland Clinic
  • Medical News Today

Filed Under: Causes

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